APCONIX LTD
Redx Pharma is the company ApconiX provided project toxicology support and ion channel screening data.
Project Toxicology and Ion Channel Screening for Redx Pharma
Redx Pharma is a drug discovery and development company focused on creating new drugs for areas such as cancer and immunology. Redx recognised a need for expert safety input and ion channel screening data to develop high quality clinical candidates.
Through this relationship, Redx had access to the entire team of nonclinical safety experts. Our experts worked closely with Redx scientists, to provide guidance on nonclinical safety and DMPK strategy, as well as gap analysis, data interpretation and advice on next steps. For the lead programs entering GLP toxicity studies, we worked with Redx to influence study design and decision-making, as well as data interpretation. We co-authored the submission documents and participated in regulatory agency interactions.
In this extremely successful partnership, we have developed a model relationship with Redx Pharma. For the two most advanced projects, one was successfully divested to a US biotech, and the other achieved a successful CTA.
Company details
- Industry:
- Biotechnology and pharmaceuticals
“ApconiX has provided hERG data to Redx Pharma from June 2016 to help support our discovery projects. Data turnaround times over this period have been rapid (under 1 week) and this has been critical in progressing projects quickly; outsourcing the assay with this turn-around has had no impact on our “design-make-test” cycle times. Additionally, ApconiX’s approach is very collaborative providing expert advice on these data as part of their service. Another vital component to this screening is flexibility over compound numbers which enables us to maintain progress during the peaks and troughs of compound supply and prevents delays which can occur if you have to wait to reach a trigger point for submission of an assay.”Dr Stuart Best Redx Pharma